The evolving role of regulatory T cells in pulmonary diseases: immunomodulatory mechanisms and translational directions revealed by bibliometric analysis - Takeaways - MDSpire

The evolving role of regulatory T cells in pulmonary diseases: immunomodulatory mechanisms and translational directions revealed by bibliometric analysis

  • By

  • Qiuxia Wang

  • Jianfeng Jiang

  • Huici Yao

  • Ying Zhu

  • June 9, 2026

  • 0 min

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  • 1

    Regulatory T cells (Tregs) are crucial for immune homeostasis and play significant roles in the progression of pulmonary diseases.

  • 2

    A bibliometric analysis of 9,079 publications revealed a tri-phasic growth pattern in Treg research from 2000 to 2025.

  • 3

    The United States initially dominated Treg research, but China has become the leading contributor since 2021.

  • 4

    Keyword analyses indicated a shift from foundational immune regulation to topics like immunotherapy and chronic inflammatory lung diseases.

  • 5

    Emerging therapeutic strategies targeting Tregs and the tumor microenvironment may enhance future translational research in pulmonary diseases.

Original Source(s)

The evolving role of regulatory T cells in pulmonary diseases: immunomodulatory mechanisms and translational directions revealed by bibliometric analysis

  • by Qiuxia Wang, Jianfeng Jiang, Huici Yao, Ying Zhu

  • June 9, 2026

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