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1
Anti-LGI1 encephalitis primarily affects middle-aged individuals, with an average age of 57 years among the studied cohort.
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2
Seizures were the most common initial symptom, reported in 70% of patients, while cognitive dysfunction increased to 95% over the illness duration.
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3
Anti-LGI1 antibodies were detected in 95% of serum and 90% of cerebrospinal fluid specimens, highlighting the importance of antibody testing.
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4
Older age, prolonged diagnostic delays, and elevated antibody titers were significantly associated with unfavorable functional outcomes.
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5
Prompt dual antibody testing in serum and CSF is crucial for reducing diagnosis time and improving long-term recovery in anti-LGI1 encephalitis.
