Impact of maternal glycemic control during pregnancy on early biomarkers of neonatal metabolic syndrome - Takeaways - MDSpire

Impact of maternal glycemic control during pregnancy on early biomarkers of neonatal metabolic syndrome

  • By

  • Xiaogang An

  • Yajun Kong

  • June 25, 2026

  • 0 min

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  • 1

    The study enrolled 130 pregnant women to assess the impact of maternal glycemic control on neonatal metabolic syndrome biomarkers.

  • 2

    Neonates from the poor glycemic control group showed lower levels of tyrosine and alanine, and higher levels of total carnitine, C18 acylcarnitine, and bilirubin.

  • 3

    The incidence of neonatal hypoglycemia was significantly higher in the poor glycemic control group compared to the adequate control group.

  • 4

    After adjusting for confounders, poor maternal glycemic control was linked to decreased neonatal tyrosine and alanine, and increased total carnitine and bilirubin.

  • 5

    The findings suggest that optimizing maternal glycemic control may help mitigate early metabolic disturbances in neonates.

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