Effectiveness and Safety of Paclitaxel-Coated Balloon Angioplasty for Coronary Small Vessel Disease: A Prospective, Multicenter, Randomized Clinical Study - Takeaways - MDSpire
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Effectiveness and Safety of Paclitaxel-Coated Balloon Angioplasty for Coronary Small Vessel Disease: A Prospective, Multicenter, Randomized Clinical Study

  • By

  • Mingduo Zhang

  • Shiqi Liu

  • Zhao Ma

  • Meichen Sun

  • Yifei Nie

  • Baoen Zhang

  • Min Zhang

  • Xiantao Song

  • Dongfeng Zhang

  • March 12, 2026

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  • 1

    This study evaluates the efficacy and safety of a paclitaxel-coated balloon for treating coronary small vessel disease.

  • 2

    Patients with reference vessel diameters between 1.50 mm and 2.50 mm were included in this multicenter, randomized controlled trial.

  • 3

    The study aims to compare in-lesion late lumen loss at 9 months between the paclitaxel-coated balloon and a control group.

  • 4

    Inclusion criteria required patients to have stable or unstable angina, NSTEMI, or STEMI beyond one week.

  • 5

    Exclusion criteria included recent STEMI, significant hematologic abnormalities, and severe comorbid conditions.

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