Predictive value of perilesional edema volume in melanoma brain metastasis response to stereotactic radiosurgery - Takeaways - MDSpire

Predictive value of perilesional edema volume in melanoma brain metastasis response to stereotactic radiosurgery

  • By

  • Mariya Yavorska

  • Miriam Tomaciello

  • Antonio Sciurti

  • Elisa Cinelli

  • Giovanni Rubino

  • Armando Perrella

  • Alfonso Cerase

  • Pierpaolo Pastina

  • Giovanni Luca Gravina

  • Silvia Arcieri

  • Maria Antonietta Mazzei

  • Giuseppe Migliara

  • Valentina Baccolini

  • Francesco Marampon

  • Giuseppe Minniti

  • Anna Maria Di Giacomo

  • Paolo Tini

  • September 11, 2024

  • 0 min

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  • 1

    Melanoma brain metastases (MBMs) present significant treatment challenges due to poor prognosis and limited options.

  • 2

    Stereotactic radiotherapy (SRT) achieves local control rates of 75-95% for MBMs but still results in a median overall survival of less than one year.

  • 3

    Perilesional edema volume (PEV) is associated with cancer cell infiltration and may hinder the effectiveness of SRT and systemic therapies.

  • 4

    This study aims to evaluate the predictive value of PEV on intracranial response and survival in MBM patients treated with SRT.

  • 5

    The study utilized MRI to assess PEV and gross tumor volume, with independent evaluations to ensure accuracy in treatment response assessments.

Original Source(s)

Predictive value of perilesional edema volume in melanoma brain metastasis response to stereotactic radiosurgery

  • by Mariya Yavorska, Miriam Tomaciello, Antonio Sciurti, Elisa Cinelli, Giovanni Rubino, Armando Perrella, Alfonso Cerase, Pierpaolo Pastina, Giovanni Luca Gravina, Silvia Arcieri, Maria Antonietta Mazzei, Giuseppe Migliara, Valentina Baccolini, Francesco Marampon, Giuseppe Minniti, Anna Maria Di Giacomo, Paolo Tini

  • September 11, 2024

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