Epilepsy-Related Mortality Among Children and Adolescents - Takeaways - MDSpire
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Mortality Associated With Epilepsy in Children and Adolescents

  • By

  • Naum Shaparin

  • Rafi Khandaker

  • Jan Schwarz

  • Ali Bordbar Jahantighi

  • Lorenz Droege

  • Tina Ramishvili

  • Constance Rippel

  • Steven C. Lindo

  • Itay Tokatly Latzer

  • Jerry Chao

  • Ibraheem M. Karaye

  • October 12, 2026

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  • 1

    From 1999 through 2023, epilepsy accounted for 4472 deaths among US individuals aged 0 to 19 years.

  • 2

    Overall age-adjusted epilepsy mortality increased from 0.2 deaths per 100 000 population in 1999 to 0.4 in 2023.

  • 3

    After remaining stable from 1999 to 2001, overall epilepsy mortality increased 5.6% annually through 2023.

  • 4

    Mortality increased 8.6% annually among adolescents aged 11 to 19 years from 2008 to 2023, while rates were generally stable among children aged 10 years or younger.

  • 5

    Death certificate data may underestimate epilepsy-related deaths, and the study lacked patient-level information on comorbidities.

Original Source(s)

Epilepsy-Related Mortality Among Children and Adolescents

  • by Naum Shaparin, Rafi Khandaker, Jan Schwarz, Ali Bordbar Jahantighi, Lorenz Droege, Tina Ramishvili, Constance Rippel, Steven C. Lindo, Itay Tokatly Latzer, Jerry Chao, Ibraheem M. Karaye

  • October 12, 2026

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