A single-center observational study of nirsevimab for prevention of RSV infection in preterm infants - Takeaways - MDSpire
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An Observational Study on the Use of Nirsevimab for RSV Infection Prevention in Preterm Infants at a Single Center

  • By

  • Rina Su

  • Rigonggaowa A

  • Fang Yao

  • Yanbin An

  • Cheng Cai

  • Lei Yun

  • July 8, 2026

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  • 1

    The study evaluated nirsevimab's efficacy in preventing RSV infection in preterm infants at a single center from November 2024 to January 2026.

  • 2

    Nirsevimab immunized infants showed a significantly higher efficacy rate of 98.73% in preventing RSV infections compared to 84.81% in the non-immunized group.

  • 3

    In the non-immunized group, 15.18% of infants developed RSV infections, with some requiring respiratory support and experiencing adverse outcomes.

  • 4

    All RSV-infected infants in the non-immunized group required rehospitalization, averaging 15.5 days, while no rehospitalization occurred in the immunized group.

  • 5

    No significant adverse reactions were reported in the nirsevimab immunized group following the injection.

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