-
1
Major depressive disorder is a leading cause of disability, particularly affecting adolescents and young adults.
-
2
Suicidal behavior is a significant public health concern, with suicide being the second leading cause of death in individuals aged 15–29.
-
3
Depression with mixed features, characterized by concurrent (hypo)manic symptoms, is linked to an increased risk of suicidal behavior.
-
4
A six-month prospective cohort study was conducted to assess the predictive value of mixed features for suicide attempts in adolescents with MDD.
-
5
The study included 951 patients, with 316 meeting DSM-5 criteria for mixed features, highlighting the need for targeted prevention strategies.
