Awake surgery with direct electrical stimulation mapping and real-time cognitive monitoring for functionally guided tumor resection: how we do it - Takeaways - MDSpire

Awake surgery with direct electrical stimulation mapping and real-time cognitive monitoring for functionally guided tumor resection: how we do it

  • By

  • Fabien Almairac

  • Hugues Duffau

  • September 6, 2025

  • 0 min

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  • 1

    Awake surgery with direct electrical stimulation mapping is the gold standard for diffuse low-grade glioma and other intraparenchymal brain tumors.

  • 2

    This technique improves onco-functional outcomes, achieving less than 2% permanent deficits and approximately 94% return-to-work rates.

  • 3

    Preoperative cognitive assessments are crucial for tailoring intraoperative tasks to the patient's specific characteristics and needs.

  • 4

    Intraoperative cortical mapping involves real-time cognitive monitoring to identify functional areas that must be preserved during tumor resection.

  • 5

    The asleep–awake–asleep protocol requires strict adherence to technical principles to optimize intraoperative cognitive testing and patient outcomes.

Original Source(s)

Awake surgery with direct electrical stimulation mapping and real-time cognitive monitoring for functionally guided tumor resection: how we do it

  • by Fabien Almairac, Hugues Duffau

  • September 6, 2025

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