Editorial: Sex hormones and cardiovascular-renal health: mechanisms, consequences, and therapeutic insights - Takeaways - MDSpire

Editorial: The Role of Sex Hormones in Cardiovascular and Renal Health: Mechanisms, Implications, and Treatment Perspectives

  • By

  • Prerna Kumar

  • Evangeline Deer

  • Noha Shawky Elsayed

  • July 21, 2026

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  • 1

    Sex steroids regulate endothelial function, vascular tone, and inflammation, influencing cardiovascular risk and health outcomes.

  • 2

    Women experience increased cardiovascular disease risk during menopausal transition due to hormonal changes affecting body composition and vascular function.

  • 3

    The estimated glucose disposal rate is linked to cardiovascular risk, with higher levels associated with reduced risk of cardiovascular disease.

  • 4

    Corin levels may serve as a prognostic marker for left atrial reverse remodeling in patients with atrial fibrillation after catheter ablation.

  • 5

    The role of progesterone in cardiovascular and renal health remains unclear, necessitating further investigation into its physiological effects.

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