Preoperative NarxCare overdose risk scores greater than 100 are associated with worse PROMs improvements and dissatisfaction after primary THA - Takeaways - MDSpire

Preoperative NarxCare overdose risk scores greater than 100 are associated with worse PROMs improvements and dissatisfaction after primary THA

  • By

  • Shujaa T. Khan

  • Ahmed K. Emara

  • Shlok V. Patel

  • Khaled A. Elmenawi

  • Alvaro Ibaseta

  • Ignacio Pasqualini

  • Chao Zhang

  • Nicolas S. Piuzzi

  • June 18, 2026

  • 0 min

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  • 1

    Preoperative opioid use is linked to increased risks for complications, longer hospital stays, and higher readmission rates following total hip arthroplasty.

  • 2

    The NarxCare Overdose Risk Score (ORS) provides a nuanced measure of prescription drug use, considering multiple factors beyond simple drug use presence.

  • 3

    A NarxCare ORS exceeding 100 correlates with poorer improvements in patient-reported outcome measures (PROMs) after total hip arthroplasty.

  • 4

    The study analyzed 5424 patients who underwent primary total hip arthroplasty, excluding those with missing data or lost to follow-up.

  • 5

    Primary outcomes included achieving Minimum Clinically Important Difference (MCID) and Patient Acceptable Symptom State (PASS) thresholds in PROMs at one year.

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