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1
Cardiovascular tissues are influenced by mechanical forces that affect cell behavior, ECM organization, and disease progression.
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2
Mechanotransduction connects hemodynamics to inflammation, lipid handling, calcification, and structural failure in cardiovascular diseases.
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3
Imaging metrics like RHu can improve diagnostic accuracy in assessing calcified plaques, aiding clinical decision-making.
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4
Microcalcifications in atherosclerotic plaques can compromise cap integrity, increasing the risk of rupture through mechanical degradation.
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5
Cyclic mechanical loading is a primary driver of structural valve deterioration in bioprosthetic heart valves, overshadowing immune responses.