Intravascular ultrasound-guided percutaneous coronary intervention for syphilitic coronary ostial lesions: a single-center case series - Takeaways - MDSpire

Percutaneous Coronary Intervention Guided by Intravascular Ultrasound for Coronary Ostial Lesions Due to Syphilis: A Case Series from a Single Center

  • By

  • Yize Qi

  • Zhiyuan Wang

  • Junzhi Liu

  • Xiangdong Li

  • July 21, 2026

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  • 1

    This study evaluated the feasibility and safety of IVUS-guided PCI for syphilitic coronary artery ostial lesions (SCAOL).

  • 2

    Seven patients with confirmed SCAOL underwent PCI, with all cases diagnosed via syphilis serology and assessed using IVUS.

  • 3

    Second-generation drug-eluting stents were successfully implanted in all patients, with a median follow-up of 4 years.

  • 4

    One patient developed NSTEMI due to severe in-stent restenosis after receiving a flush-alignment stent without standardized therapy.

  • 5

    The study suggests that moderate aortic protrusion may aid in ostial coverage, but optimal stent positioning requires further investigation.

Original Source(s)

Intravascular ultrasound-guided percutaneous coronary intervention for syphilitic coronary ostial lesions: a single-center case series

  • by Yize Qi, Zhiyuan Wang, Junzhi Liu, Xiangdong Li

  • July 21, 2026

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