Amniotic membrane transplantation combined with cryotherapy vs. lamellar keratoplasty for medically refractory peripheral ulcerative keratitis: a retrospective cohort study - Takeaways - MDSpire

Amniotic membrane transplantation combined with cryotherapy vs. lamellar keratoplasty for medically refractory peripheral ulcerative keratitis: a retrospective cohort study

  • By

  • Jia Wan

  • Juan Bao

  • Cuiyu Wang

  • Ruiyao Gao

  • Kai Zhang

  • Yingxin Chen

  • June 12, 2026

  • 0 min

Share

  • 1

    This study compares amniotic membrane transplantation with cryotherapy and lamellar keratoplasty for refractory peripheral ulcerative keratitis.

  • 2

    Both surgical methods showed comparable primary ulcer healing rates, but lamellar keratoplasty had superior long-term outcomes.

  • 3

    Lamellar keratoplasty resulted in faster epithelialization, better visual acuity at 12 months, and lower recurrence rates compared to amniotic membrane transplantation.

  • 4

    Amniotic membrane transplantation demonstrated a better safety profile with no procedure-related complications, serving as a valuable bridging therapy.

  • 5

    The study highlights the importance of amniotic membrane transplantation amid global corneal donor shortages as a temporizing intervention.

Original Source(s)

Amniotic membrane transplantation combined with cryotherapy vs. lamellar keratoplasty for medically refractory peripheral ulcerative keratitis: a retrospective cohort study

  • by Jia Wan, Juan Bao, Cuiyu Wang, Ruiyao Gao, Kai Zhang, Yingxin Chen

  • June 12, 2026

Related Content

Outcomes of allogeneic ocular surface stem cell transplantation

Side Effects: Context Is the Diagnosis

This week's research makes one thing clear: who someone is before they get sick — their relationships, their partner's health, the back of their eye — is doing a lot of work medicine is only beginning to account for.

Case Report: Longitudinal analysis of local immunoregulatory mediators in a DLBCL vitreoretinal lymphoma receiving local chemotherapy