Association of Red Cell Distribution Width to Albumin Ratio (RAR) with Mortality Outcomes in ICU Patients Suffering from Sepsis-Related ARDS: A Retrospective Analysis Utilizing MIMIC-IV Data - Takeaways - MDSpire

Association of Red Cell Distribution Width to Albumin Ratio (RAR) with Mortality Outcomes in ICU Patients Suffering from Sepsis-Related ARDS: A Retrospective Analysis Utilizing MIMIC-IV Data

  • By

  • Hongzhou Wu

  • Min He

  • Yujia Gui

  • Jinyi Zhou

  • Liting Yue

  • Xiaoqin Zhang

  • February 28, 2026

  • 0 min

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  • 1

    In-hospital mortality for patients with sepsis-associated ARDS is high, reaching 43.2%, highlighting the need for early identification and intervention.

  • 2

    Red cell distribution width (RDW) is linked to inflammation and oxidative stress, and its combination with albumin (Alb) may reflect a patient's inflammatory state.

  • 3

    The study aimed to evaluate the association between the RDW-to-albumin ratio (RAR) and all-cause mortality in ICU patients with sepsis-related ARDS.

  • 4

    Data were extracted from the MIMIC-IV database, focusing on adult patients meeting ARDS and Sepsis-3 criteria, excluding those with heart failure.

  • 5

    Statistical analysis included stratifying patients by RAR quartiles and using Kaplan-Meier curves and Cox regression to assess mortality risk.

Original Source(s)

Association of Red Cell Distribution Width to Albumin Ratio (RAR) with Mortality Outcomes in ICU Patients Suffering from Sepsis-Related ARDS: A Retrospective Analysis Utilizing MIMIC-IV Data

  • by Hongzhou Wu, Min He, Yujia Gui, Jinyi Zhou, Liting Yue, Xiaoqin Zhang

  • February 28, 2026

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