Evaluation of Axillary Staging in Breast Cancer Patients After Neoadjuvant Chemotherapy: A Prognostic Study Comparing Pathological Node Staging and Lymph Node Ratio Metrics in a Series of 169 Cases - Takeaways - MDSpire

Evaluation of Axillary Staging in Breast Cancer Patients After Neoadjuvant Chemotherapy: A Prognostic Study Comparing Pathological Node Staging and Lymph Node Ratio Metrics in a Series of 169 Cases

  • By

  • Amin Safavi

  • Narjes Mohammadzadeh

  • Ahmad Kaviani

  • Anita Dadashi

  • Atousa Dadashi

  • January 30, 2026

  • 0 min

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  • 1

    The study evaluates the prognostic significance of nine axillary nodal variables in breast cancer patients after neoadjuvant chemotherapy.

  • 2

    Pathological node staging (pN-staging) and lymph node ratio (LNR) systems are compared for their ability to stratify post-NAC patients by survival risk.

  • 3

    A total of 169 breast cancer patients who received neoadjuvant chemotherapy were included in the retrospective cohort study.

  • 4

    The study highlights the potential disruption of neoadjuvant chemotherapy on traditional staging systems and survival predictability.

  • 5

    Emerging biological markers may enhance prognostic assessments alongside established clinical staging systems in breast cancer.

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