Association between red cell distribution width and HBV viral load and liver function parameters in patients with chronic hepatitis B: a real-world data study - Takeaways - MDSpire

Association between red cell distribution width and HBV viral load and liver function parameters in patients with chronic hepatitis B: a real-world data study

  • By

  • Lei Zhang

  • Chunhua Fang

  • Liping Wang

  • Bin Ran

  • May 13, 2026

  • 0 min

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  • 1

    Red cell distribution width (RDW) is significantly elevated in patients with chronic hepatitis B (CHB) compared to healthy controls.

  • 2

    Higher RDW values correlate with increased HBV viral load and liver function indicators such as ALT and AST in CHB patients.

  • 3

    Patients in the immune-active stage of CHB exhibit significantly higher RDW levels than those in the immune-tolerant/inactive stage.

  • 4

    Multivariate analysis identifies high viral load and elevated ALT as independent factors associated with increased RDW in CHB.

  • 5

    The study suggests RDW may serve as a supplementary marker for evaluating disease activity in chronic hepatitis B.

Original Source(s)

Association between red cell distribution width and HBV viral load and liver function parameters in patients with chronic hepatitis B: a real-world data study

  • by Lei Zhang, Chunhua Fang, Liping Wang, Bin Ran

  • May 13, 2026

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