The Evolution of Canaloplasty - Takeaways - MDSpire

The Evolution of Canaloplasty

Explore the latest in glaucoma surgery as innovative canaloplasty techniques enhance Schlemm's canal function and improve patient outcomes.

  • By

  • John S. McInnes, MD, JD

  • Nathan M. Radcliffe, MD

  • Cynthia Mattox, MD

  • John S. McInnes, MD, JD

  • Nathan M. Radcliffe, MD

  • Cynthia Mattox, MD

  • John S. McInnes, MD, JD

  • Nathan M. Radcliffe, MD

  • Cynthia Mattox, MD

  • May 1, 2026

  • 5 min

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  • 1

    Canaloplasty enhances Schlemm’s canal function and lowers intraocular pressure (IOP) using an implantable bioscaffold.

  • 2

    Traditional canaloplasty involves transluminal dilation of Schlemm’s canal followed by permanent scaffolding to maintain canal expansion.

  • 3

    Ab interno canaloplasty techniques are evolving to provide a bleb-free approach with favorable safety profiles and sustained IOP reduction.

  • 4

    Recent innovations include nitinol-based mechanical dilation and biologic tissue scaffolding for improved aqueous outflow.

  • 5

    Canaloplasty represents a promising addition to glaucoma surgical options, with renewed interest due to new implantable materials.

Original Source(s)

The Evolution of Canaloplasty

  • by John S. McInnes, MD, JD, Nathan M. Radcliffe, MD, Cynthia Mattox, MD, John S. McInnes, MD, JD, Nathan M. Radcliffe, MD, Cynthia Mattox, MD, John S. McInnes, MD, JD, Nathan M. Radcliffe, MD, Cynthia Mattox, MD

  • May 1, 2026

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