The Evolution of Canaloplasty - Takeaways - MDSpire

The Evolution of Canaloplasty

  • By

  • John S. McInnes, MD, JD

  • Nathan M. Radcliffe, MD

  • Cynthia Mattox, MD

  • John S. McInnes, MD, JD

  • Nathan M. Radcliffe, MD

  • Cynthia Mattox, MD

  • John S. McInnes, MD, JD

  • Nathan M. Radcliffe, MD

  • Cynthia Mattox, MD

  • May 1, 2026

  • 5 min

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  • 1

    Canaloplasty enhances Schlemm’s canal function and lowers intraocular pressure (IOP) using an implantable bioscaffold.

  • 2

    Traditional canaloplasty involves transluminal dilation of Schlemm’s canal followed by permanent scaffolding to maintain canal expansion.

  • 3

    Ab interno canaloplasty techniques are evolving to provide a bleb-free approach with favorable safety profiles and sustained IOP reduction.

  • 4

    Recent innovations include nitinol-based mechanical dilation and biologic tissue scaffolding for improved aqueous outflow.

  • 5

    Canaloplasty represents a promising addition to glaucoma surgical options, with renewed interest due to new implantable materials.

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