Case Report: A rare case of esophageal squamous cell carcinoma with metastases to the pancreas and stomach - Takeaways - MDSpire

Case Report: A rare case of esophageal squamous cell carcinoma with metastases to the pancreas and stomach

  • By

  • Yuhang Lv

  • Yanting Jiang

  • Kaiyuan Hui

  • Xiaodong Jiang

  • June 11, 2026

  • 0 min

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  • 1

    Esophageal squamous cell carcinoma (ESCC) is a highly aggressive cancer with a poor prognosis and common distant metastases.

  • 2

    Metastasis of ESCC to the pancreas and stomach is extremely rare, with pancreatic metastases accounting for less than 2% of pancreatic neoplasms.

  • 3

    A 62-year-old male developed pancreatic and gastric metastases 37 months after radiotherapy for ESCC, highlighting the need for differential diagnosis.

  • 4

    The patient underwent radical surgical resection followed by immunochemotherapy, suggesting a viable treatment strategy for atypical metastatic presentations.

  • 5

    This case emphasizes the importance of considering rare metastases in patients with a history of ESCC, even after a prolonged disease-free interval.

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