Association between red blood cell transfusion and adverse clinical outcomes is Independent of cardiac history: a multicenter observational InPUT study analysis - Takeaways - MDSpire

Association between red blood cell transfusion and adverse clinical outcomes is Independent of cardiac history: a multicenter observational InPUT study analysis

  • By

  • Antoine Kimmoun

  • Nicolas Girerd

  • Kevin Duarte

  • Jolie Bruno

  • Jimmy Schenk

  • Bruno Levy

  • Guillaume Baudry

  • Senta Jorinde Raasveld

  • Sanne de Bruin

  • Merijn C. Reuland

  • Claudia van den Oord

  • Caroline M. Schaap

  • Jan Bakker

  • Maurizio Cecconi

  • Aarne Feldheiser

  • Jens Meier

  • Zoe McQuilten

  • Marcella C. A. Müller

  • Thomas W. L. Scheeren

  • Cécile Aubron

  • Andrew W. J. Flint

  • Tarikul Hamid

  • Michaël Piagnerelli

  • Tina Tomić Mahečić

  • Jan Benes

  • Lene Russell

  • Hernan Aguirre-Bermeo

  • Konstantina Triantafyllopoulou

  • Vasiliki Chantziara

  • Mohan Gurjar

  • Sheila Nainan Myatra

  • Vincenzo Pota

  • Muhammed Elhadi

  • Ryszard Gawda

  • Mafalda Mourisco

  • Marcus Lance

  • Vojislava Neskovic

  • Matej Podbregar

  • Juan V. Llau

  • Manual Quintana-Diaz

  • Maria Cronhjort

  • Carmen A. Pfortmueller

  • Nihan Yapici

  • Nathan Nielsen

  • Akshay Shah

  • Harm-Jan de Grooth

  • Alexander P. J. Vlaar

  • Alexandre Mebazaa

  • December 18, 2025

  • 0 min

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  • 1

    Red blood cell transfusion is common in intensive care, with 25-50% of patients receiving at least one unit during their stay.

  • 2

    Anaemia affects up to 60% of ICU patients at admission and up to 90% during their stay, often leading to RBC transfusions.

  • 3

    Current guidelines recommend a restrictive transfusion strategy, but adherence is low, especially among patients with cardiac history.

  • 4

    The InPUT study analyzed the impact of RBC transfusion on clinical outcomes, focusing on patients with a documented cardiac history.

  • 5

    The study found that cardiac history does not significantly influence the association between RBC transfusion and adverse clinical outcomes.

Original Source(s)

Association between red blood cell transfusion and adverse clinical outcomes is Independent of cardiac history: a multicenter observational InPUT study analysis

  • by Antoine Kimmoun, Nicolas Girerd, Kevin Duarte, Jolie Bruno, Jimmy Schenk, Bruno Levy, Guillaume Baudry, Senta Jorinde Raasveld, Sanne de Bruin, Merijn C. Reuland, Claudia van den Oord, Caroline M. Schaap, Jan Bakker, Maurizio Cecconi, Aarne Feldheiser, Jens Meier, Zoe McQuilten, Marcella C. A. Müller, Thomas W. L. Scheeren, Cécile Aubron, Andrew W. J. Flint, Tarikul Hamid, Michaël Piagnerelli, Tina Tomić Mahečić, Jan Benes, Lene Russell, Hernan Aguirre-Bermeo, Konstantina Triantafyllopoulou, Vasiliki Chantziara, Mohan Gurjar, Sheila Nainan Myatra, Vincenzo Pota, Muhammed Elhadi, Ryszard Gawda, Mafalda Mourisco, Marcus Lance, Vojislava Neskovic, Matej Podbregar, Juan V. Llau, Manual Quintana-Diaz, Maria Cronhjort, Carmen A. Pfortmueller, Nihan Yapici, Nathan Nielsen, Akshay Shah, Harm-Jan de Grooth, Alexander P. J. Vlaar, Alexandre Mebazaa

  • December 18, 2025

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