Psychiatric and Sleep Disorders in Patients With Nonfunctional Adrenal Tumors - Takeaways - MDSpire

Psychiatric and Sleep Disorders in Patients With Nonfunctional Adrenal Tumors

  • By

  • Hadis Mirzaei

  • Jonatan D Lindh

  • Buster Mannheimer

  • Henrik Falhammar

  • September 19, 2025

  • 0 min

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  • 1

    Patients with nonfunctional adrenal tumors (NFATs) have a higher prevalence of psychiatric and sleep disorders compared to controls.

  • 2

    The study found an increased incidence of psychiatric and sleep disorders in NFAT patients during a median follow-up of 5.4 years.

  • 3

    Previous psychiatric and sleep disorders were more common in NFAT patients, with an adjusted odds ratio of 2.06.

  • 4

    Secondary outcomes, including mood, anxiety, and substance abuse disorders, also showed increased prevalence in NFAT patients.

  • 5

    The findings suggest that NFATs may contribute to mental health issues, potentially due to subtle cortisol dysregulation.

Original Source(s)

Psychiatric and Sleep Disorders in Patients With Nonfunctional Adrenal Tumors

  • by Hadis Mirzaei, Jonatan D Lindh, Buster Mannheimer, Henrik Falhammar

  • September 19, 2025

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