Putting the PASC Score to the Test: Clinical vs. Statistical Accuracy in Long COVID Diagnosis - Takeaways - MDSpire

Putting the PASC Score to the Test: Clinical vs. Statistical Accuracy in Long COVID Diagnosis

  • By

  • Alba Azola

  • Raha M. Dastgheyb

  • Rebecca Easter

  • Hannah Parker

  • Christina Della Penna

  • Isabel Santiuste

  • Holly Schultz

  • Ana Ehrenspeck

  • Rebecca Veenhuis

  • Leah H. Rubin

  • November 17, 2025

  • 0 min

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  • 1

    Long COVID affects approximately 6.9% of US adults, translating to over 22 million individuals experiencing debilitating symptoms.

  • 2

    The National Academies of Sciences defined long COVID as an infection-associated chronic condition with symptoms lasting at least three months.

  • 3

    The RECOVER initiative identified 12 key symptoms that differentiate SARS-CoV-2 infected individuals from uninfected ones for diagnosing long COVID.

  • 4

    A PASC score of 12 or higher was established as the cutoff to categorize individuals as having Post-Acute Sequelae of SARS-CoV-2 infection.

  • 5

    The study aimed to validate the PASC score in a specialized long COVID clinic to enhance diagnostic accuracy and clinical applicability.

Original Source(s)

Putting the PASC Score to the Test: Clinical vs. Statistical Accuracy in Long COVID Diagnosis

  • by Alba Azola, Raha M. Dastgheyb, Rebecca Easter, Hannah Parker, Christina Della Penna, Isabel Santiuste, Holly Schultz, Ana Ehrenspeck, Rebecca Veenhuis, Leah H. Rubin

  • November 17, 2025

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