Nipple or skin-sparing mastectomy flap: can preoperative breast-MRI predict post-operative complications? - Takeaways - MDSpire
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Can Preoperative Breast MRI Predict Complications After Nipple- or Skin-Sparing Mastectomy?

  • By

  • L. I. Sgaramella

  • A. Pasculli

  • F. P. Prete

  • F. Cofone

  • M. Moschetta

  • M. Maruccia

  • R. Elia

  • M. Telegrafo

  • V. De Ruvo

  • M. Bisceglie

  • M. M. Miccoli

  • F. Palma

  • C. Testini

  • G. Giudice

  • M. Testini

  • A. Gurrado

  • October 13, 2026

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  • 1

    This single-center retrospective study assessed whether preoperative MRI flap thickness and demographic characteristics predicted complications after nipple- or skin-sparing mastectomy.

  • 2

    Eligible patients underwent preoperative breast MRI and immediate implant-based, one- or two-stage reconstruction for breast cancer or a BRCA1/2 mutation.

  • 3

    Patients were grouped according to mean preoperative MRI skin-flap thickness below or above 8 mm.

  • 4

    The same experienced surgeons performed all mastectomies, assessing flap viability clinically without routine intraoperative perfusion imaging.

  • 5

    The study aimed to compare early postoperative complications between patients with MRI flap thicknesses below and above 8 mm.

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