Prealbumin Levels as a Predictor of Subsequent Liver Metastases in Colorectal Cancer - Takeaways - MDSpire

Prealbumin Levels as a Predictor of Subsequent Liver Metastases in Colorectal Cancer

  • By

  • Han-bing Xie

  • Bei-bei Zhang

  • Lin Zhao

  • Le Liu

  • Ping-ping Liu

  • Xin Zhang

  • Shi-di Miao

  • Rui-tao Wang

  • Hai-tao Xu

  • November 25, 2025

  • 0 min

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  • 1

    Colorectal cancer is the third most common cancer globally, with the liver being the primary site for metastasis.

  • 2

    Prealbumin levels are associated with nutritional status and can predict adverse outcomes in colorectal cancer patients.

  • 3

    This study evaluated 627 patients who underwent curative resection for CRC to determine the predictive value of prealbumin for liver metastases.

  • 4

    Lower prealbumin levels were significantly associated with the occurrence of metachronous liver metastases in both primary and validation cohorts.

  • 5

    Patients with advanced tumor stages and positive lymph node involvement exhibited lower prealbumin levels compared to those without liver metastases.

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