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1
Immune checkpoint inhibitors can induce severe immune-related adverse events, including the life-threatening 3M syndrome.
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2
3M syndrome is characterized by the combination of immune myocarditis, myositis, and myasthenia gravis, leading to high mortality.
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3
Early symptoms of 3M syndrome, such as ptosis and facial weakness, are often subtle and can be misattributed to other conditions.
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4
A 65-year-old female patient developed 3M syndrome after anti-PD-1 therapy for cervical cancer, resulting in acute heart failure.
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5
Proactive monitoring and immediate immunosuppressive treatment are essential for managing the risks associated with immunotherapy.