Differential effects of transcatheter edge-to-edge repair on forward stroke volume in atrial and ventricular secondary mitral regurgitation - Takeaways - MDSpire

Differential effects of transcatheter edge-to-edge repair on forward stroke volume in atrial and ventricular secondary mitral regurgitation

  • By

  • Franziska Grewe

  • Luise Ulrich

  • Moritz Haus

  • Philippe Felfeli

  • Christian Schach

  • Andreas Luchner

  • Christoph Birner

  • Lars S. Maier

  • Bernhard Unsöld

  • Christine Meindl

  • Kurt Debl

  • Michael Paulus

  • June 8, 2026

  • 0 min

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  • 1

    Transcatheter edge-to-edge mitral valve repair (M-TEER) is recommended for patients with severe secondary ventricular mitral regurgitation at high surgical risk.

  • 2

    Forward stroke volume (FSV) may serve as a more accurate marker for assessing left ventricular dysfunction compared to left ventricular ejection fraction (LVEF).

  • 3

    Atrial mitral regurgitation (MR) is increasingly recognized as a distinct phenotype, often occurring in patients with preserved left ventricular function.

  • 4

    The study investigated the early effects of M-TEER on FSV and its predictive value for outcomes like all-cause mortality and heart failure hospitalization.

  • 5

    Echocardiographic assessments were performed at baseline and 4 weeks post-M-TEER to evaluate MR severity and left ventricular function.

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