Evidence of nosocomial human-to-human transmission of Dabie bandavirus: a clinical, epidemiological, and virological investigation - Takeaways - MDSpire
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Investigating Human-to-Human Transmission of Dabie Bandavirus in Healthcare Settings: Clinical, Epidemiological, and Virological Insights

  • By

  • Shan Hong

  • Kai Li

  • Jingqi Yang

  • Xianfang Peng

  • Tianshu Cao

  • Yufei Xie

  • Yongqiang Deng

  • Mengxu Sun

  • Qi Chen

  • Xiang Chen

  • Aiping Wu

  • Hangyu Zhou

  • Shengjun Wu

  • Xingyao Huang

  • Chengfeng Qin

  • August 31, 2026

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  • 1

    Dabie bandavirus (DBV) causes severe fever with thrombocytopenia syndrome (SFTS), which has an estimated case fatality rate of 12% to 50%.

  • 2

    Although ticks are the primary transmission vector, DBV can spread between humans, likely through direct contact with infectious body fluids or unprotected ocular exposure.

  • 3

    Whole-genome sequencing can help verify a shared viral origin, distinguish related transmission clusters from unrelated introductions, and support outbreak reconstruction.

  • 4

    A Zhejiang Province hospital cluster comprised one index patient and five secondary cases, including four healthcare workers and one patient who shared the index patient’s ward.

  • 5

    The study integrated contact tracing, clinical data, viral isolation, microneutralization assays, and whole-genome sequencing to investigate nosocomial DBV transmission.

Original Source(s)

Evidence of nosocomial human-to-human transmission of Dabie bandavirus: a clinical, epidemiological, and virological investigation

  • by Shan Hong, Kai Li, Jingqi Yang, Xianfang Peng, Tianshu Cao, Yufei Xie, Yongqiang Deng, Mengxu Sun, Qi Chen, Xiang Chen, Aiping Wu, Hangyu Zhou, Shengjun Wu, Xingyao Huang, Chengfeng Qin

  • August 31, 2026

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