Weight Loss, Comorbidity, and Complications After Single-anastomosis Sleeve Ileal Bypass (SASI): A Systematic Review and Meta-analysis - Takeaways - MDSpire

Weight Loss, Comorbidity, and Complications After Single-anastomosis Sleeve Ileal Bypass (SASI): A Systematic Review and Meta-analysis

  • By

  • Helene Marie Haug

  • Hilde Risstad

  • Rolf Eikeland Hagen

  • Tom Mala

  • Jon Adalsteinn Kristinsson

  • Torgeir Thorson Søvik

  • June 24, 2026

  • 0 min

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  • 1

    Metabolic bariatric surgery is the most effective intervention for achieving substantial weight loss and improving metabolic disease.

  • 2

    Single-anastomosis sleeve ileal bypass (SASI) is a newly developed surgical technique that may offer substantial weight loss and metabolic improvements.

  • 3

    Initial studies suggest outcomes of SASI may be comparable to or exceed those of established bariatric procedures, but concerns about nutritional deficiencies remain.

  • 4

    The systematic review aims to update evidence on SASI's effects on weight reduction, type 2 diabetes remission, dyslipidemia, and nutritional status.

  • 5

    Eligibility criteria for included studies focused on adults with obesity, surgical intervention of SASI, and outcomes related to weight loss and nutritional changes.

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