Butterfly gliomas: to biopsy or to ablate – a longitudinal cohort study - Takeaways - MDSpire

Butterfly gliomas: to biopsy or to ablate – a longitudinal cohort study

  • By

  • Vratko Himic

  • Morgan Leigh Johnson

  • Anshul Ratnaparkhi

  • Roxanne C. Mayrand

  • Jay Chandar

  • Vaidya Govindarajan

  • Daniel C. Kreatsoulas

  • Arman Jahangiri

  • Zachary C. Gersey

  • Daniel M. Aaronson

  • Ricardo J. Komotar

  • Micheal E. Ivan

  • Ashish H. Shah

  • June 5, 2026

  • 0 min

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  • 1

    Butterfly gliomas are aggressive gliomas with poor prognosis, accounting for 3–14% of glioblastomas and median survival of 3.2 to 6.3 months.

  • 2

    Surgical resection may provide survival benefits over biopsy alone, but carries risks of significant neurological morbidity.

  • 3

    Laser interstitial thermal therapy (LITT) is a minimally invasive treatment option that may enhance immune activation and reduce surgical morbidity.

  • 4

    The study compares outcomes of biopsy versus LITT in patients with butterfly glioma, focusing on survival, complications, and neurological function.

  • 5

    Ethical approval for the study was granted, allowing retrospective analysis without explicit informed patient consent.

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