Impact of spread through air spaces (STAS) and lymphovascular invasion (LVI) on prognosis in NSCLC: a comprehensive pathological evaluation - Takeaways - MDSpire

Impact of spread through air spaces (STAS) and lymphovascular invasion (LVI) on prognosis in NSCLC: a comprehensive pathological evaluation

  • By

  • Can Kutlay

  • Selim Şakir Erkmen Gülhan

  • Leyla Nesrin Acar

  • Muhyettin Aslan

  • Fatma Benli Tanrıkulu

  • April 9, 2025

  • 0 min

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  • 1

    Spread through air spaces (STAS) is a significant independent pathological feature affecting prognosis in non-small cell lung cancer (NSCLC).

  • 2

    Lymphovascular invasion (LVI) is associated with increased risk of nodal spread and distant metastasis, leading to poorer outcomes in NSCLC patients.

  • 3

    The study reevaluated pathology specimens from 352 NSCLC patients to assess the impact of STAS and LVI on recurrence and overall survival rates.

  • 4

    Statistical analysis revealed that age, lymph node invasion, stage, and STAS significantly affected recurrence-free and overall survival.

  • 5

    The presence of STAS was noted in 59.1% of cases, indicating its high prevalence, particularly in adenocarcinoma types.

Original Source(s)

Impact of spread through air spaces (STAS) and lymphovascular invasion (LVI) on prognosis in NSCLC: a comprehensive pathological evaluation

  • by Can Kutlay, Selim Şakir Erkmen Gülhan, Leyla Nesrin Acar, Muhyettin Aslan, Fatma Benli Tanrıkulu

  • April 9, 2025

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