Clinical efficacy analysis of natural orifice specimen extraction surgery (NOSES) and conventional laparoscopic surgery (CLS) in the treatment of rectal cancer: a single-center retrospective analysis - Takeaways - MDSpire
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Comparative Study of Natural Orifice Specimen Extraction Surgery (NOSES) Versus Conventional Laparoscopic Surgery (CLS) for Rectal Cancer Treatment: A Retrospective Analysis from a Single Center

  • By

  • Kai Deng

  • Yi-ran Li

  • Teng-long Guo

  • Jun-zhe Dou

  • Yu-liang Cui

  • Ying-feng Su

  • July 13, 2025

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  • 1

    Colorectal cancer is the third most common cancer globally, necessitating effective surgical treatments to improve patient outcomes.

  • 2

    Natural orifice specimen extraction surgery (NOSES) offers a minimally invasive option for rectal cancer, potentially reducing postoperative pain and complications.

  • 3

    This study analyzed 221 rectal cancer patients, comparing outcomes between NOSES (24 patients) and conventional laparoscopic surgery (CLS, 197 patients).

  • 4

    Key treatment indicators evaluated included surgical time, blood loss, VAS scores, hospital stay, and complications to assess the efficacy of each surgical approach.

  • 5

    The study's findings aim to provide an evidence-based foundation for selecting surgical approaches in rectal cancer treatment.

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