Characteristics and Treatment Patterns of Early Stage Melanoma: Results from a Multisite Chart Review - Takeaways - MDSpire
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Analysis of Early Stage Melanoma Management and Treatment Approaches: Findings from a Multicenter Chart Review

  • By

  • Collin M. Costello

  • Maria L. Wei

  • James Isaacs

  • Elizabeth M. Gaughan

  • Adina Greene

  • Alexandra So

  • Xiaochen Zhong

  • Jara Majuelos-Melguizo

  • Kavita Gandhi

  • Claudia Rey

  • Alicia Delibes

  • Rosemarie Barnett

  • Mizuho Fukunaga-Kalabis

  • Nawab Qizilbash

  • Irene M. Shui

  • Xiang-Lin Tan

  • September 19, 2026

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  • 1

    Early-stage cutaneous melanoma (IB–IIC) is primarily managed through surgery, often with sentinel lymph node biopsy, per NCCN guidelines.

  • 2

    As melanoma stage increases, systemic drug therapy and radiotherapy usage rise, with systemic therapy being predominant in second-line treatments.

  • 3

    Higher-stage melanoma is linked to receiving more treatment lines, indicating a need for novel therapies and optimized treatment sequencing.

  • 4

    The study aimed to characterize real-world treatment patterns for early-stage melanoma, highlighting gaps in current research and practice.

  • 5

    The investigation involved four US institutions and focused on patients aged ≥ 18 years with newly diagnosed stage IB–IIC melanoma.

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