Immunometabolic Contributions of Atopobiaceae Family Members in Human Papillomavirus Infection, Cervical Dysplasia, and Cancer - Takeaways - MDSpire

Immunometabolic Contributions of Atopobiaceae Family Members in Human Papillomavirus Infection, Cervical Dysplasia, and Cancer

  • By

  • Nicole R Jimenez

  • Vianney Mancilla

  • Paweł Łaniewski

  • Melissa M Herbst-Kralovetz

  • November 1, 2024

  • 0 min

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  • 1

    Atopobiaceae family members are linked to HPV persistence and cervical cancer progression in the cervicovaginal environment.

  • 2

    Higher prevalence of Atopobiaceae was found in Hispanic women with increased gravidity and parity.

  • 3

    Fannyhessea species were associated with high-risk HPV genotypes 31 and 52, indicating a potential role in cancer development.

  • 4

    Atopobiaceae profiles correlated with elevated proinflammatory cytokines and cancer biomarkers, suggesting immune modulation.

  • 5

    The study highlights Atopobiaceae as potential targets for monitoring HPV persistence and preventing HPV-related cancers.

Original Source(s)

Immunometabolic Contributions of Atopobiaceae Family Members in Human Papillomavirus Infection, Cervical Dysplasia, and Cancer

  • by Nicole R Jimenez, Vianney Mancilla, Paweł Łaniewski, Melissa M Herbst-Kralovetz

  • November 1, 2024

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