Initiation of an emergency department discharge pathway for low-risk patients with venous thromboembolism: Factors impact real-world practice

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Venous thromboembolism (VTE) is the third most common cardiovascular disorder, with an annual incidence of one in 1000 persons.
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The incidence of VTE has increased in the US and Europe over the last two decades, with many patients eligible for home treatment not receiving it.
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A comprehensive institutional pathway for outpatient treatment of low-risk VTE patients was implemented on July 1, 2016.
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The pathway included outpatient guidance, follow-up scheduling, and anticoagulant education facilitated by clinical pharmacists.
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A natural language processing tool was developed to accurately identify VTE diagnoses, demonstrating a positive predictive value of 94%.

Vascular Medicine

by William B Stubblefield, James Barclay, Jesse O Wrenn, Doug Conway, Scott Nelson, Quinn S Wells, Dario Giuse, Zhao Zuo, Alexandra M Baird, Tyler Barrett, Shi Huang, Karen Beauchamp, Alan B Storrow, Sean P Collins, Joshua A Beckman
July 6, 2026

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