Bidirectional association between COPD and AF: a systematic review and meta-analysis - Takeaways - MDSpire

Bidirectional association between COPD and AF: a systematic review and meta-analysis

  • By

  • Yunmeng Wang

  • Chaowei Ding

  • Yawei Liu

  • Jingchao Lu

  • June 19, 2026

  • 0 min

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  • 1

    The study evaluates the bidirectional association between chronic obstructive pulmonary disease (COPD) and atrial fibrillation (AF).

  • 2

    A total of 48 publications were included, revealing that AF increases the risk of COPD and vice versa, with odds ratios of 1.56 and 1.72, respectively.

  • 3

    AF in COPD patients is linked to higher short-term and long-term mortality risks, with odds ratios of 1.76 and 1.27, respectively.

  • 4

    COPD in AF patients also correlates with increased mortality risks, with short-term and long-term odds ratios of 1.54 and 1.68.

  • 5

    The findings suggest a need for integrated management strategies for patients with comorbid COPD and AF, emphasizing their combined impact on prognosis.

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