Evaluating Ultrasound as a Predictor of Pathological Response to Neoadjuvant Chemotherapy in Breast Cancer Patients: A Systematic Review and Meta-Analysis - Takeaways - MDSpire

Evaluating Ultrasound as a Predictor of Pathological Response to Neoadjuvant Chemotherapy in Breast Cancer Patients: A Systematic Review and Meta-Analysis

  • By

  • Qing Feng Shi

  • Peng Fei Hu

  • Yong Hong Liu

  • January 13, 2026

  • 0 min

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  • 1

    Neoadjuvant chemotherapy (NAC) in breast cancer reduces tumor burden and may improve surgical outcomes.

  • 2

    Ultrasound (US) imaging is increasingly used to predict pathological response to NAC in breast cancer patients.

  • 3

    A systematic review and meta-analysis evaluated the effectiveness of US as a predictor of NAC response in breast cancer.

  • 4

    Seventy-two studies involving 8439 patients were included, highlighting the variability in US techniques and outcomes.

  • 5

    Quality assessment revealed significant risks of bias in patient selection and testing methods across the included studies.

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