High Rates of Mortality During Drug-Resistant Tuberculosis Treatment Among Individuals With Diabetes Mellitus and Low Body Mass Index

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Diabetes significantly increases the risk of mortality during rifampicin-resistant tuberculosis (RR-TB) treatment.
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Individuals with low body mass index (BMI <18.5 kg/m2) also face higher mortality rates during RR-TB treatment.
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The highest mortality rates occur in patients with both diabetes and low BMI during RR-TB treatment.
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The study analyzed data from 345 adults treated for RR-TB in Indonesia between March 2020 and May 2022.
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No significant interaction was found between diabetes and low BMI affecting mortality rates during RR-TB treatment.

Open Forum Infectious Diseases

by Lara D Veeken, Iceu D Kulsum, Bony W Lestari, Prayudi Santoso, Nanny N M Soetedjo, Raspati C Koesoemadinata, Adriana V Miranda, Wini Sukmawati, Argita D Salindri, Arto Y Soeroto, Reinout van Crevel
June 25, 2025

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