Non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio is associated with cardiovascular outcomes after percutaneous coronary intervention in patients with type 2 diabetes - Takeaways - MDSpire

Non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio is associated with cardiovascular outcomes after percutaneous coronary intervention in patients with type 2 diabetes

  • By

  • Xi He

  • Guanlian He

  • Liqin Qi

  • Yujie Chen

  • Zhaorong Lin

  • Wenjia Chen

  • Qintao Huang

  • Libin Liu

  • Zhaoyang Chen

  • Ruonan Gao

  • May 15, 2026

  • 0 min

Share

  • 1

    The study examined the relationship between the non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio (NHHR) and major adverse cardiovascular events (MACEs).

  • 2

    In a cohort of 1176 adults with type 2 diabetes undergoing PCI, higher NHHR was linked to increased MACE risk, with significant hazard ratios in higher quartiles.

  • 3

    A 1-unit increase in NHHR within a specific range raised MACE risk by 1.4-fold, indicating a nonlinear association between NHHR and cardiovascular outcomes.

  • 4

    The NHHR showed strong prognostic value for predicting post-PCI MACEs, with an area under the ROC curve of 0.84 when combined with the Global Registry of Acute Coronary Events risk score.

  • 5

    Routine assessment of NHHR may enhance early risk identification and personalized care for type 2 diabetes patients undergoing PCI.

Original Source(s)

Non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio is associated with cardiovascular outcomes after percutaneous coronary intervention in patients with type 2 diabetes

  • by Xi He, Guanlian He, Liqin Qi, Yujie Chen, Zhaorong Lin, Wenjia Chen, Qintao Huang, Libin Liu, Zhaoyang Chen, Ruonan Gao

  • May 15, 2026

Related Content

Exposure to heavy metals and trace elements and risk of dyslipidemia: a nested case-control analysis in rural adults

Drug-coated balloons vs. drug-eluting stents for coronary artery disease: an updated systematic review and meta-analysis of randomized controlled trials with lesion-specific insights

School-Based Screening Detected Undiagnosed Hypertension

Novel program enabled large-scale blood pressure screening and identified elevated readings in community setting.