Single-catheter radiofrequency pulmonary vein isolation for atrial fibrillation: a comparative evaluation - Takeaways - MDSpire
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Evaluation of Single-Catheter Radiofrequency Ablation for Pulmonary Vein Isolation in Atrial Fibrillation: A Comparative Study

  • By

  • Alessio Falasca Zamponi

  • Fariborz Tabrizi

  • Anders Englund

  • Sergej Scheel

  • Jens Olson

  • Ivar Skoger

  • Christian Basile

  • Raffaele Scorza

  • June 15, 2026

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  • 1

    The study evaluated the efficacy and efficiency of single-catheter radiofrequency ablation for pulmonary vein isolation in atrial fibrillation.

  • 2

    A CMC-free cohort showed significantly shorter procedures, reduced fluoroscopy time, and lower radiation doses compared to the CMC-guided cohort.

  • 3

    Twelve-month freedom from atrial arrhythmia was comparable between CMC-guided and CMC-free groups, indicating similar efficacy.

  • 4

    The CMC-free approach demonstrated improved procedural efficiency without compromising safety or effectiveness in first-time PVI.

  • 5

    Further prospective randomized studies are needed to confirm the findings and assess the safety and efficacy of omitting CMC in ablation.

Original Source(s)

Single-catheter radiofrequency pulmonary vein isolation for atrial fibrillation: a comparative evaluation

  • by Alessio Falasca Zamponi, Fariborz Tabrizi, Anders Englund, Sergej Scheel, Jens Olson, Ivar Skoger, Christian Basile, Raffaele Scorza

  • June 15, 2026

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