Variations in Cervical Cancer Incidence Trends Adjusted for Hysterectomy Across Different Age Groups in Puerto Rico, 2001-2023

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Puerto Rico has high cervical cancer incidence rates, with a 4.5% annual increase in late-stage cases from 2001 to 2019.
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From 2001 to 2023, hysterectomy-corrected cervical cancer incidence rates exceeded 11.5 cases per 100,000 women.
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Significant increases in cervical cancer incidence were observed among women aged 35 to 49 years, with an AAPC of 2.0%.
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Cervical cancer incidence among women younger than 35 years decreased significantly by 20.2% from 2019 to 2023, likely due to HPV vaccination.
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The study highlights the need for public health interventions for women aged 35 to 49 years, as screening uptake remains stable despite health service disruptions.

Jama Network Open

by Ana P. Ortiz, Jeslie M. Ramos-Cartagena, Carlos R. Torres-Cintrón, Eduardo J. Santiago-Rodríguez, Sandra I. García-Camacho, Ashish A. Deshmukh, Karen J. Ortiz-Ortiz
April 29, 2026

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