Hybrid eclipse: a case of isolated renal tuberculosis with an unusual infectious–inflammatory–neoplastic triad - Takeaways - MDSpire

Uncommon Presentation of Isolated Renal Tuberculosis with a Distinct Infectious-Inflammatory-Neoplastic Triad

  • By

  • Sachin Dharwadkar

  • Vijaykumar Ramu

  • Kavitha B. Chittaragi

  • Suchitha Sathish

  • Sudha Kiran Das

  • Sajan Sehgal

  • July 17, 2026

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  • 1

    Isolated renal tuberculosis is a rare extrapulmonary manifestation that often mimics urinary tract infections, leading to delayed diagnosis.

  • 2

    A 77-year-old diabetic man presented with left loin pain and chronic lumbar sinus discharge, revealing complex renal pathologies.

  • 3

    Multiphase CT showed renal replacement lipomatosis, a hyperenhancing mass suggestive of clear cell renal cell carcinoma, and signs of renal tuberculosis.

  • 4

    Radical nephrectomy confirmed renal tuberculosis and its complications, including a perinephric abscess and nephrocutaneous fistula.

  • 5

    Postoperative antitubercular therapy resulted in stable clinical outcomes, highlighting the importance of early imaging and diagnosis.

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