The Role of Low Dose Whole Body CT in the Detection of Progression of Patients with Smoldering Multiple Myeloma - Takeaways - MDSpire

The Role of Low Dose Whole Body CT in the Detection of Progression of Patients with Smoldering Multiple Myeloma

  • By

  • Maria Gavriatopoulou

  • Andriani Βoultadaki

  • Vassilis Koutoulidis

  • Ioannis Ntanasis-Stathopoulos

  • Charis Bourgioti

  • Panagiotis Malandrakis

  • Despina Fotiou

  • Magdalini Migkou

  • Nikolaos Kanellias

  • Evangelos Eleutherakis-Papaiakovou

  • Efstathios Kastritis

  • Evangelos Terpos

  • Meletios A. Dimopoulos

  • Lia-Angela Moulopoulos

  • September 25, 2020

  • 0 min

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  • 1

    Smoldering multiple myeloma (SMM) has a 10% annual risk of progression to symptomatic disease, necessitating effective monitoring.

  • 2

    Whole-body low-dose CT (WBLDCT) is now included in the IMWG diagnostic criteria for detecting progression in asymptomatic multiple myeloma.

  • 3

    WBLDCT is more sensitive than conventional radiography in identifying small osteolytic lesions, crucial for diagnosing active multiple myeloma.

  • 4

    The study evaluated 100 patients with asymptomatic MM, using WBLDCT to assess disease progression over a median of 2.5 exams.

  • 5

    Technological advancements have reduced radiation exposure in WBLDCT, making it a viable option for regular monitoring of multiple myeloma.

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