Endogenous Testosterone, Testosterone Treatment, and Cardiovascular Health Outcomes in Men - Takeaways - MDSpire

Endogenous Testosterone, Testosterone Treatment, and Cardiovascular Health Outcomes in Men

  • By

  • Bu B Yeap

  • Bradley D Anawalt

  • November 12, 2025

  • 0 min

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  • 1

    Lower testosterone levels in aging men are linked to poorer cardiovascular health, but causation remains unclear.

  • 2

    The UK Biobank study found lower testosterone levels associated with higher all-cause mortality, but not with cardiovascular events.

  • 3

    Testosterone treatment in men with dysglycemia reduced type 2 diabetes risk, indicating potential metabolic benefits.

  • 4

    The TRAVERSE trial showed no increased cardiovascular risk with testosterone treatment in men with existing CVD.

  • 5

    Further research is needed to confirm long-term cardiovascular safety and explore benefits of testosterone on body composition.

Original Source(s)

Endogenous Testosterone, Testosterone Treatment, and Cardiovascular Health Outcomes in Men

  • by Bu B Yeap, Bradley D Anawalt

  • November 12, 2025

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