Non-exposure LECS (CLEAN-NET) for gastric cancer: long-term outcomes of a function-preserving strategy with selective nodal assessment - Takeaways - MDSpire

Non-exposure LECS (CLEAN-NET) for gastric cancer: long-term outcomes of a function-preserving strategy with selective nodal assessment

  • By

  • Manabu Onimaru

  • Haruhiro Inoue

  • Kenta Nakahara

  • Koji Otsuka

  • Yoshio Deguchi

  • Noboru Yokoyama

  • July 14, 2026

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  • 1

    Gastric cancer is a leading cause of cancer-related mortality globally, with treatment options including ESD and standard gastrectomy.

  • 2

    LECS combines endoscopic and laparoscopic techniques to enable precise local resection while preserving gastric anatomy.

  • 3

    CLEAN-NET is a non-exposure technique that allows full-thickness resection without opening the gastric lumen, reducing tumor spillage risk.

  • 4

    This study evaluates long-term outcomes of CLEAN-NET for gastric cancer, providing follow-up data extending up to 16.8 years.

  • 5

    Patients selected for CLEAN-NET had early-stage gastric cancer, and treatment decisions were based on tumor and patient-related factors.

Original Source(s)

Non-exposure LECS (CLEAN-NET) for gastric cancer: long-term outcomes of a function-preserving strategy with selective nodal assessment

  • by Manabu Onimaru, Haruhiro Inoue, Kenta Nakahara, Koji Otsuka, Yoshio Deguchi, Noboru Yokoyama

  • July 14, 2026

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