Screening of adolescents for testicular cancer-a nationwide retrospective cohort study - Takeaways - MDSpire

Screening of adolescents for testicular cancer-a nationwide retrospective cohort study

  • By

  • Yair Zloof

  • Tomer Erlich

  • Maya Braun

  • Ruth Lev Bar-Or

  • Dotan Yaari

  • Emmanuel S Sirat

  • Lidor Peretz

  • Arik Eisenkraft

  • Limor Friedensohn

  • Gilad Twig

  • Amir Shlaifer

  • November 3, 2025

  • 0 min

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  • 1

    Testicular cancer is the most common malignancy in males aged 15 to 34 years, with a rising incidence in recent decades.

  • 2

    A nationwide study of 300,793 Israeli males aged 16 to 21 assessed the effectiveness of clinical testicular examinations before military service.

  • 3

    The study identified 43 cases of testicular cancer during 1,172,603 person-years of follow-up, yielding an incidence rate of 3.67 per 100,000 person-years.

  • 4

    Screening sensitivity was low at 66.7% and 40% at 6 and 12 months, respectively, indicating ineffective routine screening for asymptomatic adolescents.

  • 5

    Findings suggest that the high number needed to screen and frequent unnecessary evaluations do not support routine testicular cancer screening in this population.

Original Source(s)

Screening of adolescents for testicular cancer-a nationwide retrospective cohort study

  • by Yair Zloof, Tomer Erlich, Maya Braun, Ruth Lev Bar-Or, Dotan Yaari, Emmanuel S Sirat, Lidor Peretz, Arik Eisenkraft, Limor Friedensohn, Gilad Twig, Amir Shlaifer

  • November 3, 2025

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