Case Report: Rare factor V inhibitor found in a patient with ulcerative colitis during latent tuberculosis infection - Takeaways - MDSpire
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Uncommon Factor V Inhibitor Detected in a Patient with Ulcerative Colitis and Latent Tuberculosis Infection: A Case Study

  • By

  • Yaodong Wang

  • Na Li

  • Xiaoxin Li

  • Jinchun He

  • June 2, 2026

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  • 1

    Acquired factor V deficiency (AFVD) is characterized by a relative deficiency of coagulation factor V due to internal FV inhibitors.

  • 2

    Infection is a common secondary cause of FV inhibitors, complicating the diagnosis of AFVD.

  • 3

    The case study reports a patient with ulcerative colitis and latent tuberculosis infection who had high-titer FV inhibitors.

  • 4

    Immunomodulatory treatment with intravenous immunoglobulin successfully eliminated FV inhibitors and improved the patient's symptoms.

  • 5

    This case is the first report of FV inhibitor in patients with ulcerative colitis during latent tuberculosis infection.

Original Source(s)

Case Report: Rare factor V inhibitor found in a patient with ulcerative colitis during latent tuberculosis infection

  • by Yaodong Wang, Na Li, Xiaoxin Li, Jinchun He

  • June 2, 2026

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