Partial Oral Therapy for Infective Endocarditis Among Adult Infectious Diseases Physicians in the United States: An Emerging Infections Network Survey - Takeaways - MDSpire

Partial Oral Therapy for Infective Endocarditis Among Adult Infectious Diseases Physicians in the United States: An Emerging Infections Network Survey

  • By

  • Jack W McHugh

  • Larry M Baddour

  • Supavit Chesdachai

  • Susan E Beekmann

  • Philip M Polgreen

  • Walter R Wilson

  • Daniel C DeSimone

  • September 15, 2025

  • 0 min

Share

  • 1

    Partial oral therapy (POT) for infective endocarditis (IE) is infrequently used by U.S. adult infectious diseases physicians.

  • 2

    Only 10% of surveyed physicians used POT in more than 25% of their IE cases, indicating limited adoption.

  • 3

    Physicians' comfort with POT varied by pathogen, with 66% comfortable for Streptococcus spp. and only 19% for methicillin-resistant Staphylococcus aureus.

  • 4

    Key barriers to POT adoption included fear of relapse (72%) and adherence concerns (53%), while availability of oral agents was a major facilitator.

  • 5

    There is a strong desire among physicians for clearer guidelines and additional data to support the use of POT in treating infective endocarditis.

Original Source(s)

Partial Oral Therapy for Infective Endocarditis Among Adult Infectious Diseases Physicians in the United States: An Emerging Infections Network Survey

  • by Jack W McHugh, Larry M Baddour, Supavit Chesdachai, Susan E Beekmann, Philip M Polgreen, Walter R Wilson, Daniel C DeSimone

  • September 15, 2025

Related Content

Gold Nanostars Take SERS Inside the Biofilm

Steven Bell explains how – and why – he’s tracking antibiotic diffusion in living biofilms

Staphylococcus aureus serine protease-like protein B elicits a type 1/type 2 immune response in atopic dermatitis patients

Antibiotic Guideline Gaps Raise SSI Risk

Nonadherence to IDSA/SIS/SHEA perioperative antibiotic prophylaxis guidelines associated with significantly higher surgical site infection rates, finds nationwide analysis.