Mild Hyponatremia After TJA: Safe to Discharge? - Takeaways - MDSpire

Mild Hyponatremia After TJA: Safe to Discharge?

Associations with medical and overall complications were largely driven by acute kidney injury in a retrospective single-center study

  • By

  • Andrea Surnit

  • May 6, 2026

  • 4 min

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  • 1

    Mild postoperative hyponatremia occurred in 21% of patients after total joint arthroplasty, with sodium levels defined as below 135 mEq/L.

  • 2

    Patients with postoperative hyponatremia had higher odds of medical and overall complications, primarily driven by acute kidney injury.

  • 3

    Excluding acute kidney injury, postoperative hyponatremia was not associated with increased medical or overall complications.

  • 4

    No significant differences in surgical outcomes or rates of unplanned readmissions were found between hyponatremic and normonatremic patients.

  • 5

    The study suggests that asymptomatic mildly hyponatremic patients may be safely discharged without incurring additional management costs.

Original Source(s)

Mild Hyponatremia After TJA: Safe to Discharge?

  • by Andrea Surnit

  • May 6, 2026

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