Predicting the outcome of normal pressure hydrocephalus therapy—where do we stand? - Takeaways - MDSpire

Predicting the outcome of normal pressure hydrocephalus therapy—where do we stand?

  • By

  • Joachim M. K. Oertel

  • Matthias J. M. Huelser

  • January 20, 2021

  • 0 min

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  • 1

    Normal-pressure hydrocephalus (NPH) is a treatable form of dementia, with shunt insertion as the gold standard therapy.

  • 2

    Approximately 85% of patients respond positively to shunt treatment, but predicting non-responders remains challenging.

  • 3

    Positive predictors for treatment response include spinal tab tests and continuous lumbar drainage, despite low negative predictive values.

  • 4

    Radiological findings, such as the DESH sign and anterior callosal angle, may correlate with treatment outcomes, but results are inconsistent.

  • 5

    Individualized decision-making is crucial, weighing positive and negative predictors to ensure patients receive appropriate therapy.

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