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1
Normal-pressure hydrocephalus (NPH) is a treatable form of dementia, with shunt insertion as the gold standard therapy.
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2
Approximately 85% of patients respond positively to shunt treatment, but predicting non-responders remains challenging.
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3
Positive predictors for treatment response include spinal tab tests and continuous lumbar drainage, despite low negative predictive values.
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4
Radiological findings, such as the DESH sign and anterior callosal angle, may correlate with treatment outcomes, but results are inconsistent.
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5
Individualized decision-making is crucial, weighing positive and negative predictors to ensure patients receive appropriate therapy.