Endoscopic mucosal resection versus endoscopic submucosal dissection for early colorectal cancer and precursor lesions: a retrospective study - Takeaways - MDSpire

Endoscopic mucosal resection versus endoscopic submucosal dissection for early colorectal cancer and precursor lesions: a retrospective study

  • By

  • Mengyuan Yang

  • Chanjuan Fan

  • Zhen Li

  • Liangqin Pan

  • Jianping Cheng

  • July 1, 2026

  • 0 min

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  • 1

    This study compared endoscopic mucosal resection (EMR) and endoscopic submucosal dissection (ESD) for early colorectal cancer and precursor lesions.

  • 2

    A total of 101 patients were enrolled, with 53 undergoing EMR and 48 undergoing ESD based on lesion characteristics.

  • 3

    For lesions ≥20 mm, ESD demonstrated significantly higher en bloc, complete, and curative resection rates compared to EMR.

  • 4

    ESD was associated with a higher complication rate in the right colon compared to EMR, particularly for larger lesions.

  • 5

    At 12-month follow-up, recurrence rates were lower for ESD (2.1%) compared to EMR (11.3%), though the difference was not statistically significant.

Original Source(s)

Endoscopic mucosal resection versus endoscopic submucosal dissection for early colorectal cancer and precursor lesions: a retrospective study

  • by Mengyuan Yang, Chanjuan Fan, Zhen Li, Liangqin Pan, Jianping Cheng

  • July 1, 2026

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